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A potent tetravalent T-cell–engaging bispecific antibody against CD33 in acute myeloid leukemia

Acute myeloid leukemia (AML), the most common acute leukemia in adults and the second most common cancer in children, is still a lethal disease in the majority of patients, but immunologic approaches have improved outcome. Bispecific antibodies (BsAbs) are novel immunotherapeutics that can redirect...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Hoseini, Sayed Shahabuddin, Guo, Hongfen, Wu, Zhihao, Hatano, Miho Nakajima, Cheung, Nai-Kong V.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998923/
https://ncbi.nlm.nih.gov/pubmed/29858209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017014373
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