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Development of a tetravalent anti-GPA33/anti-CD3 bispecific antibody for colorectal cancers
Despite progress in the treatment of colorectal cancer (CRC), curing metastatic CRC (mCRC) remains a major unmet medical need worldwide. Here we described a T cell engaging bispecific antibody (T-BsAb) to redirect polyclonal cytotoxic T cells to eradicate CRC. A33, a murine antibody specific for GPA...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Cancer Ther |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168351/ https://ncbi.nlm.nih.gov/pubmed/30082472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0026 |
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