Loading...
Structural design of disialoganglioside GD2 and CD3-bispecific antibodies to redirect T cells for tumor therapy
Antibody based immunotherapy has proven efficacy for patients with high risk neuroblastoma. However, despite being the most efficient tumoricidal effectors, T cells are underutilized because they lack Fc receptors. Using a monovalent single chain fragment (ScFv) platform, we engineered tandem scFv b...
Na minha lista:
| Udgivet i: | Int J Cancer |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517675/ https://ncbi.nlm.nih.gov/pubmed/24895182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29007 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|