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T cell engaging bispecific antibody (T-BsAb): from technology to therapeutics

Harnessing the power of the human immune system to treat cancer is the essence of immunotherapy. Monoclonal antibodies engage the innate immune system to destroy targeted cells. For the last 30 years, antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity have been the m...

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Bibliographic Details
Published in:Pharmacol Ther
Main Authors: Wu, Zhihao, Cheung, Nai-Kong V.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785550/
https://ncbi.nlm.nih.gov/pubmed/28834699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.08.005
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