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Plk1 phosphorylation of Topors is involved in its degradation
Topors is a DNA topoisomerase I- and p53-binding protein, and mainly functions as a p53 regulator. Accumulating evidence also supports the notion that Topors plays the role as a negative regulator of cell growth, and possibly as a tumor suppressor. Here, we demonstrated that Topors is also involved...
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| Publié dans: | Mol Biol Rep |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4965875/ https://ncbi.nlm.nih.gov/pubmed/19821153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-009-9871-1 |
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