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Plk1 phosphorylation of Topors is involved in its degradation

Topors is a DNA topoisomerase I- and p53-binding protein, and mainly functions as a p53 regulator. Accumulating evidence also supports the notion that Topors plays the role as a negative regulator of cell growth, and possibly as a tumor suppressor. Here, we demonstrated that Topors is also involved...

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Detalhes bibliográficos
Publicado no:Mol Biol Rep
Main Authors: Yang, Xiaoming, Li, Hongchang, Deng, Anping, Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965875/
https://ncbi.nlm.nih.gov/pubmed/19821153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-009-9871-1
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