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Plk1 Phosphorylation of TRF1 Is Essential for Its Binding to Telomeres

In a search for Polo-like kinase 1 (Plk1) interaction proteins, we have identified TRF1 (telomeric repeat binding factor 1) as a potential Plk1 target. In this communication we report further characterization of the interaction. We show that Plk1 associates with TRF1, and Plk1 phosphorylates TRF1 at...

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Detalhes bibliográficos
Main Authors: Wu, Zhao-Qiu, Yang, Xiaoming, Weber, Gregory, Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533076/
https://ncbi.nlm.nih.gov/pubmed/18625707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803304200
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