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Plk1-mediated Phosphorylation of Topors Regulates p53 Stability
Polo-like kinase 1 (Plk1) overexpression is associated with tumorigenesis by an unknown mechanism. Likewise, Plk1 was suggested to act as a negative regulator of tumor suppressor p53, but the mechanism remains to be determined. Herein, we have identified topoisomerase I-binding protein (Topors), a p...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707202/ https://ncbi.nlm.nih.gov/pubmed/19473992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.001560 |
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