Phosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore–microtubule attachments

CLIP-170 is implicated in the formation of kinetochore–microtubule attachments through direct interaction with the dynein/dynactin complex. However, whether this important function of CLIP-170 is regulated by phosphorylation is unknown. Herein, we have identified polo-like kinase 1 (Plk1) and casein...

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Main Authors: Li, Hongchang, Liu, X Shawn, Yang, Xiaoming, Wang, Yingmin, Wang, Yun, Turner, Jerrold R, Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944045/
https://ncbi.nlm.nih.gov/pubmed/20664522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.174
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