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Phosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore–microtubule attachments

CLIP-170 is implicated in the formation of kinetochore–microtubule attachments through direct interaction with the dynein/dynactin complex. However, whether this important function of CLIP-170 is regulated by phosphorylation is unknown. Herein, we have identified polo-like kinase 1 (Plk1) and casein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Hongchang, Liu, X Shawn, Yang, Xiaoming, Wang, Yingmin, Wang, Yun, Turner, Jerrold R, Liu, Xiaoqi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944045/
https://ncbi.nlm.nih.gov/pubmed/20664522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.174
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