The Lys(63)-deubiquitylating Enzyme BRCC36 Limits DNA Break Processing and Repair

Multisubunit protein assemblies offer integrated functionalities for efficient cell signal transduction control. One example of such protein assemblies, the BRCA1-A macromolecular complex, couples ubiquitin recognition and metabolism and promotes cellular responses to DNA damage. Specifically, the B...

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Vydáno v:J Biol Chem
Hlavní autoři: Ng, Hoi-Man, Wei, Leizhen, Lan, Li, Huen, Michael S. Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965568/
https://ncbi.nlm.nih.gov/pubmed/27288411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731927
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