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The Lys(63)-specific Deubiquitinating Enzyme BRCC36 Is Regulated by Two Scaffold Proteins Localizing in Different Subcellular Compartments

BRCC36 is a member of the JAMM/MPN(+) family of zinc metalloproteases that specifically cleaves Lys 63-linked polyubiquitin chains in vitro. We and others showed previously that BRCC36 is a component of the BRCA1-A complex, which consists of RAP80, CCDC98/ABRAXAS, BRCC45/BRE, MERIT40/NBA1, BRCC36, a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Feng, Lin, Wang, Jiadong, Chen, Junjie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945589/
https://ncbi.nlm.nih.gov/pubmed/20656690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135392
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