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Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury

BACKGROUND: Ischemia/reperfusion (I/R) is an important cause of acute renal failure and delayed graft function, and it may induce chronic renal damage by activating epithelial to mesenchymal transition (EMT) of renal tubular cells. Heparanase (HPSE), an endoglycosidase that regulates FGF-2 and TGFβ-...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Masola, Valentina, Zaza, Gianluigi, Gambaro, Giovanni, Onisto, Maurizio, Bellin, Gloria, Vischini, Gisella, Khamaysi, Iyad, Hassan, Ahmad, Hamoud, Shadi, Nativ, Omri, N. Heyman, Samuel, Lupo, Antonio, Vlodavsky, Israel, Abassi, Zaid
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965068/
https://ncbi.nlm.nih.gov/pubmed/27467172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160074
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