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Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545

Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase, an endoglycosidase that cleaves heparan sulf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Abassi, Zaid, Hamoud, Shadi, Hassan, Ahmad, Khamaysi, Iyad, Nativ, Omri, Heyman, Samuel N., Muhammad, Rabia Shekh, Ilan, Neta, Singh, Preeti, Hammond, Edward, Zaza, Gianluigi, Lupo, Antonio, Onisto, Maurizio, Bellin, Gloria, Masola, Valentina, Vlodavsky, Israel, Gambaro, Giovani
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470960/
https://ncbi.nlm.nih.gov/pubmed/28388547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16573
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