Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545

Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase, an endoglycosidase that cleaves heparan sulf...

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Udgivet i:Oncotarget
Main Authors: Abassi, Zaid, Hamoud, Shadi, Hassan, Ahmad, Khamaysi, Iyad, Nativ, Omri, Heyman, Samuel N., Muhammad, Rabia Shekh, Ilan, Neta, Singh, Preeti, Hammond, Edward, Zaza, Gianluigi, Lupo, Antonio, Onisto, Maurizio, Bellin, Gloria, Masola, Valentina, Vlodavsky, Israel, Gambaro, Giovani
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470960/
https://ncbi.nlm.nih.gov/pubmed/28388547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16573
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