Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury

Renal ischemia/reperfusion (I/R) injury occurs in patients undergoing renal transplantation and with acute kidney injury and is responsible for the development of chronic allograft dysfunction as characterized by parenchymal alteration and fibrosis. Heparanase (HPSE), an endoglycosidase that regulat...

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Pubblicato in:Oncotarget
Autori principali: Masola, Valentina, Bellin, Gloria, Vischini, Gisella, Dall'Olmo, Luigi, Granata, Simona, Gambaro, Giovanni, Lupo, Antonio, Onisto, Maurizio, Zaza, Gianluigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281411/
https://ncbi.nlm.nih.gov/pubmed/30546836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26324
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