Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury

Renal ischemia/reperfusion (I/R) injury occurs in patients undergoing renal transplantation and with acute kidney injury and is responsible for the development of chronic allograft dysfunction as characterized by parenchymal alteration and fibrosis. Heparanase (HPSE), an endoglycosidase that regulat...

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Publicat a:Oncotarget
Autors principals: Masola, Valentina, Bellin, Gloria, Vischini, Gisella, Dall'Olmo, Luigi, Granata, Simona, Gambaro, Giovanni, Lupo, Antonio, Onisto, Maurizio, Zaza, Gianluigi
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281411/
https://ncbi.nlm.nih.gov/pubmed/30546836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26324
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