Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury

Renal ischemia/reperfusion (I/R) injury occurs in patients undergoing renal transplantation and with acute kidney injury and is responsible for the development of chronic allograft dysfunction as characterized by parenchymal alteration and fibrosis. Heparanase (HPSE), an endoglycosidase that regulat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Masola, Valentina, Bellin, Gloria, Vischini, Gisella, Dall'Olmo, Luigi, Granata, Simona, Gambaro, Giovanni, Lupo, Antonio, Onisto, Maurizio, Zaza, Gianluigi
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281411/
https://ncbi.nlm.nih.gov/pubmed/30546836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26324
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