Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury

BACKGROUND: Ischemia/reperfusion (I/R) is an important cause of acute renal failure and delayed graft function, and it may induce chronic renal damage by activating epithelial to mesenchymal transition (EMT) of renal tubular cells. Heparanase (HPSE), an endoglycosidase that regulates FGF-2 and TGFβ-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Masola, Valentina, Zaza, Gianluigi, Gambaro, Giovanni, Onisto, Maurizio, Bellin, Gloria, Vischini, Gisella, Khamaysi, Iyad, Hassan, Ahmad, Hamoud, Shadi, Nativ, Omri, N. Heyman, Samuel, Lupo, Antonio, Vlodavsky, Israel, Abassi, Zaid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965068/
https://ncbi.nlm.nih.gov/pubmed/27467172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160074
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