TSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being

The steroidogenic 18 kDa translocator protein (TSPO) is an emerging, attractive therapeutic tool for several pathological conditions of the nervous system. Here, 13 high affinity TSPO ligands belonging to our previously described N,N-dialkyl-2-phenylindol-3-ylglyoxylamide (PIGA) class were evaluated...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Da Pozzo, Eleonora, Giacomelli, Chiara, Costa, Barbara, Cavallini, Chiara, Taliani, Sabrina, Barresi, Elisabetta, Da Settimo, Federico, Martini, Claudia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964404/
https://ncbi.nlm.nih.gov/pubmed/27367681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071028
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