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Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
The BubR1/Bub3 complex is an important regulator of chromosome segregation as it facilitates proper kinetochore–microtubule interactions and is also an essential component of the spindle assembly checkpoint (SAC). Whether BubR1/Bub3 localization to kinetochores in human cells stimulates SAC signalli...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963475/ https://ncbi.nlm.nih.gov/pubmed/27457023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12256 |
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