Loading...
Ni-Catalyzed Enantioselective C-Acylation of α-Substituted Lactams
A new strategy for the catalytic enantioselective C-acylation to generate α-quaternary substituted lactams is reported. Ni-catalyzed three-component coupling of lactam enolates, benzonitriles, and aryl halides produce β-imino lactams that then afford β-keto lactams by acid hydrolysis. Use of a readi...
Na minha lista:
| Udgivet i: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963289/ https://ncbi.nlm.nih.gov/pubmed/27373124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b02120 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|