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Catalytic Enantioselective Alkylation of Substituted Dioxanone Enol Ethers. Ready Access to C(α)-Tetrasubstituted Hydroxyketones, Acids, and Esters

The catalytic enantioselective formation of tetrasubstituted α-alkoxycarbonyl compounds is an ongoing challenge to synthetic chemists.[1] Fully-substituted α-hydroxyesters and acids comprise essential components of, and building blocks for, many bioactive natural products. These include quinic acid...

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Detalhes bibliográficos
Main Authors: Seto, Masaki, Roizen, Jennifer L., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762748/
https://ncbi.nlm.nih.gov/pubmed/18651681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200801424
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