Extracellular adenosine production by ecto-5′-nucleotidase (CD73) enhances radiation-induced lung fibrosis

Radiation-induced pulmonary fibrosis is a severe side effect of thoracic irradiation, but its pathogenesis remains poorly understood and no effective treatment is available. In this study, we investigated the role of the extracellular adenosine as generated by the ecto-5'-nucleotidase CD73 in f...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wirsdörfer, Florian, de Leve, Simone, Cappuccini, Federica, Eldh, Therese, Meyer, Alina V., Gau, Eva, Thompson, Linda F., Chen, Ning-Yuan, Karmouty-Quintana, Harry, Fischer, Ute, Kasper, Michael, Klein, Diana, Ritchey, Jerry W., Blackburn, Michael R., Westendorf, Astrid M., Stuschke, Martin, Jendrossek, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960984/
https://ncbi.nlm.nih.gov/pubmed/26921334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2310
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