Extracellular adenosine production by ecto-5′-nucleotidase (CD73) enhances radiation-induced lung fibrosis

Radiation-induced pulmonary fibrosis is a severe side effect of thoracic irradiation, but its pathogenesis remains poorly understood and no effective treatment is available. In this study, we investigated the role of the extracellular adenosine as generated by the ecto-5'-nucleotidase CD73 in f...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Wirsdörfer, Florian, de Leve, Simone, Cappuccini, Federica, Eldh, Therese, Meyer, Alina V., Gau, Eva, Thompson, Linda F., Chen, Ning-Yuan, Karmouty-Quintana, Harry, Fischer, Ute, Kasper, Michael, Klein, Diana, Ritchey, Jerry W., Blackburn, Michael R., Westendorf, Astrid M., Stuschke, Martin, Jendrossek, Verena
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960984/
https://ncbi.nlm.nih.gov/pubmed/26921334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2310
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