Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

BACKGROUND: Lymphocyte infiltration is a common feature of radiation-induced pneumonitis and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we addressed the impact of thorax irradiation on the T cell compartment with a focus on immunosuppressive regulatory T cel...

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Detalhes bibliográficos
Main Authors: Wirsdörfer, Florian, Cappuccini, Federica, Niazman, Muska, de Leve, Simone, Westendorf, Astrid M, Lüdemann, Lutz, Stuschke, Martin, Jendrossek, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011772/
https://ncbi.nlm.nih.gov/pubmed/24766907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-9-98
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