Extracellular adenosine production by ecto-5′-nucleotidase (CD73) enhances radiation-induced lung fibrosis

Radiation-induced pulmonary fibrosis is a severe side effect of thoracic irradiation, but its pathogenesis remains poorly understood and no effective treatment is available. In this study, we investigated the role of the extracellular adenosine as generated by the ecto-5'-nucleotidase CD73 in f...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Wirsdörfer, Florian, de Leve, Simone, Cappuccini, Federica, Eldh, Therese, Meyer, Alina V., Gau, Eva, Thompson, Linda F., Chen, Ning-Yuan, Karmouty-Quintana, Harry, Fischer, Ute, Kasper, Michael, Klein, Diana, Ritchey, Jerry W., Blackburn, Michael R., Westendorf, Astrid M., Stuschke, Martin, Jendrossek, Verena
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960984/
https://ncbi.nlm.nih.gov/pubmed/26921334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2310
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