Extracellular adenosine production by ecto-5′-nucleotidase (CD73) enhances radiation-induced lung fibrosis

Radiation-induced pulmonary fibrosis is a severe side effect of thoracic irradiation, but its pathogenesis remains poorly understood and no effective treatment is available. In this study, we investigated the role of the extracellular adenosine as generated by the ecto-5'-nucleotidase CD73 in f...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Wirsdörfer, Florian, de Leve, Simone, Cappuccini, Federica, Eldh, Therese, Meyer, Alina V., Gau, Eva, Thompson, Linda F., Chen, Ning-Yuan, Karmouty-Quintana, Harry, Fischer, Ute, Kasper, Michael, Klein, Diana, Ritchey, Jerry W., Blackburn, Michael R., Westendorf, Astrid M., Stuschke, Martin, Jendrossek, Verena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960984/
https://ncbi.nlm.nih.gov/pubmed/26921334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2310
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge