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Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome

WW domains are small domains present in many human proteins with a wide array of functions and acting through the recognition of proline-rich sequences. The WW domain belonging to polyglutamine tract-binding protein 1 (PQBP1) is of particular interest due to its direct involvement in several X chrom...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Pucheta-Martinez, Encarna, D’Amelio, Nicola, Lelli, Moreno, Martinez-Torrecuadrada, Jorge L., Sudol, Marius, Saladino, Giorgio, Gervasio, Francesco Luigi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960638/
https://ncbi.nlm.nih.gov/pubmed/27456546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30293
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