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Dominant folding pathways of a WW domain

We investigate the folding mechanism of the WW domain Fip35 using a realistic atomistic force field by applying the Dominant Reaction Pathways approach. We find evidence for the existence of two folding pathways, which differ by the order of formation of the two hairpins. This result is consistent w...

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Main Authors: a Beccara, Silvio, Škrbić, Tatjana, Covino, Roberto, Faccioli, Pietro
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289289/
https://ncbi.nlm.nih.gov/pubmed/22308345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111796109
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