Structure–function–folding relationship in a WW domain

Protein folding barriers result from a combination of factors including unavoidable energetic frustration from nonnative interactions, natural variation and selection of the amino acid sequence for function, and/or selection pressure against aggregation. The rate-limiting step for human Pin1 WW doma...

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Bibliographische Detailangaben
Hauptverfasser: Jäger, Marcus, Zhang, Yan, Bieschke, Jan, Nguyen, Houbi, Dendle, Maria, Bowman, Marianne E., Noel, Joseph P., Gruebele, Martin, Kelly, Jeffery W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502286/
https://ncbi.nlm.nih.gov/pubmed/16807295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600511103
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