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Sequence determinants of thermodynamic stability in a WW domain—An all-β-sheet protein
The stabilities of 66 sequence variants of the human Pin1 WW domain have been determined by equilibrium thermal denaturation experiments. All 34 residues composing the hPin1 WW three-stranded β-sheet structure could be replaced one at a time with at least one different natural or non-natural amino a...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776968/ https://ncbi.nlm.nih.gov/pubmed/19565466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.172 |
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