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High-resolution mapping of the folding transition state of a WW domain

Fast-folding WW domains are among the best-characterized systems for comparing experiments and simulations of protein folding. Recent microsecond-resolution experiments and long (totaling milliseconds) single-trajectory modeling have shown that even mechanistic changes due to mutation in folding kin...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Dave, Kapil, Jäger, Marcus, Nguyen, Houbi, Kelly, Jeffery W., Gruebele, Martin
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835268/
https://ncbi.nlm.nih.gov/pubmed/26880334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.02.008
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