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The Role of Non-Native Interactions in the Folding of Knotted Proteins
Stochastic simulations of coarse-grained protein models are used to investigate the propensity to form knots in early stages of protein folding. The study is carried out comparatively for two homologous carbamoyltransferases, a natively-knotted N-acetylornithine carbamoyltransferase (AOTCase) and an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375218/ https://ncbi.nlm.nih.gov/pubmed/22719235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002504 |
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