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Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome
WW domains are small domains present in many human proteins with a wide array of functions and acting through the recognition of proline-rich sequences. The WW domain belonging to polyglutamine tract-binding protein 1 (PQBP1) is of particular interest due to its direct involvement in several X chrom...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960638/ https://ncbi.nlm.nih.gov/pubmed/27456546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30293 |
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