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Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding

Shiga toxin (Stx), an AB(5) toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells whereas LPLs with small head g...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ailte, Ieva, Lingelem, Anne Berit Dyve, Kavaliauskiene, Simona, Bergan, Jonas, Kvalvaag, Audun Sverre, Myrann, Anne-Grethe, Skotland, Tore, Sandvig, Kirsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960542/
https://ncbi.nlm.nih.gov/pubmed/27458147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30336
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