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Protection against Shiga Toxins

Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by furin and transported retrogradely to the Golgi apparatus and to the endoplasmi...

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Detalles Bibliográficos
Publicado en:Toxins (Basel)
Autores principales: Kavaliauskiene, Simona, Dyve Lingelem, Anne Berit, Skotland, Tore, Sandvig, Kirsten
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331424/
https://ncbi.nlm.nih.gov/pubmed/28165371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9020044
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