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Protection against Shiga Toxins

Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by furin and transported retrogradely to the Golgi apparatus and to the endoplasmi...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Kavaliauskiene, Simona, Dyve Lingelem, Anne Berit, Skotland, Tore, Sandvig, Kirsten
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331424/
https://ncbi.nlm.nih.gov/pubmed/28165371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9020044
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