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Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells

The heat shock protein 90 (Hsp90) inhibitor geldanamycin (GA) has been shown to alter endosomal sorting, diverting cargo destined for the recycling pathway into the lysosomal pathway. Here we investigated whether GA also affects the sorting of cargo into the retrograde pathway from endosomes to the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Lingelem, Anne Berit Dyve, Hjelseth, Ieva Ailte, Simm, Roger, Torgersen, Maria Lyngaas, Sandvig, Kirsten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445914/
https://ncbi.nlm.nih.gov/pubmed/26017782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129214
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