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Role of Phospholipase A(2) in Retrograde Transport of Ricin

Ricin is a protein toxin classified as a bioterror agent, for which there are no known treatment options available after intoxication. It is composed of an enzymatically active A-chain connected by a disulfide bond to a cell binding B-chain. After internalization by endocytosis, ricin is transported...

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Bibliographic Details
Main Authors: Klokk, Tove Irene, Lingelem, Anne Berit Dyve, Myrann, Anne-Grethe, Sandvig, Kirsten
Format: Artigo
Language:Inglês
Published: MDPI 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202871/
https://ncbi.nlm.nih.gov/pubmed/22069763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3091203
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