The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport

2-hydroxyoleic acid (OHOA, Minerval(®)) is an example of a substance used for membrane lipid therapy, where the cellular membranes rather than specific proteins constitute the therapeutical target. OHOA is thought to mediate its anti-tumor effect by affecting the biophysical properties of membranes,...

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Udgivet i:Oncotarget
Main Authors: Torgersen, Maria L., Klokk, Tove Irene, Kavaliauskiene, Simona, Klose, Christian, Simons, Kai, Skotland, Tore, Sandvig, Kirsten
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349960/
https://ncbi.nlm.nih.gov/pubmed/27894086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13508
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