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Improved Incorporation of Noncanonical Amino Acids by an Engineered tRNA(Tyr) Suppressor
The Methanocaldcoccus jannaschii tyrosyl-tRNA synthetase (TyrRS):tRNA(Tyr) cognate pair has been used to incorporate a large number of noncanonical amino acids (ncAAs) into recombinant proteins in Escherichia coli. However, the structural elements of the suppressor tRNA(Tyr) used in these experiment...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959848/ https://ncbi.nlm.nih.gov/pubmed/26694948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01185 |
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