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Rationally evolving tRNA(Pyl) for efficient incorporation of noncanonical amino acids
Genetic encoding of noncanonical amino acids (ncAAs) into proteins is a powerful approach to study protein functions. Pyrrolysyl-tRNA synthetase (PylRS), a polyspecific aminoacyl-tRNA synthetase in wide use, has facilitated incorporation of a large number of different ncAAs into proteins to date. To...
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| 發表在: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4678846/ https://ncbi.nlm.nih.gov/pubmed/26250114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv800 |
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