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Effect of acidic pH on the stability of α–Synuclein dimers

Environmental factors, such as acidic pH, facilitate the assembly of α-synuclein (α-Syn) in aggregates, but the impact of pH on the very first step of α-Syn aggregation remains elusive. Recently, we developed a single-molecule approach enabling us to measure directly the stability of α-Syn dimers. U...

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Bibliographic Details
Published in:Biopolymers
Main Authors: Lv, Zhengjian, Krasnoslobodtsev, Alexey V., Zhang, Yuliang, Ysselstein, Daniel, Rochet, Jean-Christophe, Blanchard, Scott C., Lyubchenko, Yuri L.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958566/
https://ncbi.nlm.nih.gov/pubmed/27177831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22874
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