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Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis
The aggregation of α-synuclein (α-Syn) is linked to Parkinson’s disease. The mechanism of early aggregation steps and the effect of pathogenic single-point mutations remain elusive. We report here a single-molecule fluorescence study of α-Syn dimerization and the effect of mutations. Specific intera...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407253/ https://ncbi.nlm.nih.gov/pubmed/25902443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.03.010 |
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