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Effect of Spermidine on Misfolding and Interactions of Alpha-Synuclein
Alpha-synuclein (α-Syn) is a 140 aa presynaptic protein which belongs to a group of natively unfolded proteins that are unstructured in aqueous solutions. The aggregation rate of α-Syn is accelerated in the presence of physiological levels of cellular polyamines. Here we applied single molecule AFM...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360652/ https://ncbi.nlm.nih.gov/pubmed/22662273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038099 |
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