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Effect of Spermidine on Misfolding and Interactions of Alpha-Synuclein

Alpha-synuclein (α-Syn) is a 140 aa presynaptic protein which belongs to a group of natively unfolded proteins that are unstructured in aqueous solutions. The aggregation rate of α-Syn is accelerated in the presence of physiological levels of cellular polyamines. Here we applied single molecule AFM...

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Detaylı Bibliyografya
Asıl Yazarlar: Krasnoslobodtsev, Alexey V., Peng, Jie, Asiago, Josephat M., Hindupur, Jagadish, Rochet, Jean-Christophe, Lyubchenko, Yuri L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360652/
https://ncbi.nlm.nih.gov/pubmed/22662273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038099
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