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Self-Assembly of the Full-length Amyloid Aβ42 Protein in Dimers
The self-assembly of amyloid (Aβ) proteins into nano-aggregates is a hallmark of Alzheimer’s disease (AD) development, yet the mechanism of how disordered monomers assemble into aggregates remains elusive. Here, we applied long-time molecular dynamics simulations to fully characterize the assembly o...
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| Publicado no: | Nanoscale |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114164/ https://ncbi.nlm.nih.gov/pubmed/27714140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6nr06850b |
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