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A novel pathway for amyloids self-assembly in aggregates at nanomolar concentration mediated by the interaction with surfaces
A limitation of the amyloid hypothesis in explaining the development of neurodegenerative diseases is that the level of amyloidogenic polypeptide in vivo is below the critical concentration required to form the aggregates observed in post-mortem brains. We discovered a novel, on-surface aggregation...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5372363/ https://ncbi.nlm.nih.gov/pubmed/28358113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45592 |
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