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Interaction of Aβ42 with Membranes Triggers the Self-Assembly into Oligomers

The self-assembly of amyloid β (Aβ) proteins into oligomers is the major pathogenic event leading to Alzheimer’s disease (AD). Typical in vitro experiments require high protein concentrations, whereas the physiological concentration of Aβ is in the picomolar to low nanomolar range. This complicates...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Banerjee, Siddhartha, Hashemi, Mohtadin, Zagorski, Karen, Lyubchenko, Yuri L.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036922/
https://ncbi.nlm.nih.gov/pubmed/32046252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031129
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