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High-speed atomic force microscopy reveals structural dynamics of [Formula: see text]-synuclein monomers and dimers
α-Synuclein (α-syn) is the major component of the intraneuronal inclusions called Lewy bodies, which are the pathological hallmark of Parkinson’s disease. α-Syn is capable of self-assembly into many different species, such as soluble oligomers and fibrils. Even though attempts to resolve the structu...
Enregistré dans:
| Publié dans: | J Chem Phys |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
AIP Publishing LLC
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764752/ https://ncbi.nlm.nih.gov/pubmed/29604892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5008874 |
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