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Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus

During hippocampal neuron differentiation, the expression of critical inducers of non-neuronal cell lineages must be efficiently silenced. Runx2 transcription factor is the master regulator of mesenchymal cells responsible for intramembranous osteoblast differentiation and formation of the craniofac...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Aguilar, Rodrigo, Bustos, Fernando J., Saez, Mauricio, Rojas, Adriana, Allende, Miguel L., van Wijnen, Andre J., van Zundert, Brigitte, Montecino, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958507/
https://ncbi.nlm.nih.gov/pubmed/27216774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2016.05.009
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