Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts

Expression of Runx2/p57 is a hallmark of the osteoblast-lineage identity. While several regulators that control the expression of Runx2/p57 during osteoblast lineage commitment have been identified, the epigenetic mechanisms that sustain this expression in differentiated osteoblasts remain to be com...

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Veröffentlicht in:J Cell Physiol
Hauptverfasser: Rojas, Adriana, Sepulveda, Hugo, Henriquez, Berta, Aguilar, Rodrigo, Opazo, Tatiana, Nardocci, Gino, Bustos, Fernando, Lian, Jane B., Stein, Janet L., Stein, Gary S., van Zundert, Brigitte, van Wijnen, Andre J., Allende, Miguel L., Montecino, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261149/
https://ncbi.nlm.nih.gov/pubmed/30256410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.27355
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